Hematologic side effects have rarely included eosinophilia, hypoprothrombinemia, methemoglobinemia, thrombocytopenia, neutropenia, leukopenia, agranulocytosis, and hemolytic, megaloblastic, and aplastic anemias. Hypouricemia has been associated with high-dose therapy. Thrombotic thrombocytopenic purpura and idiopathic thrombocytopenic purpura have been reported during postmarketing experience.
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